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Elizabeth M Blackwood Selected Research

GDC-0425

5/2017Phase I Study of GDC-0425, a Checkpoint Kinase 1 Inhibitor, in Combination with Gemcitabine in Patients with Refractory Solid Tumors.

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Elizabeth M Blackwood Research Topics

Disease

7Neoplasms (Cancer)
05/2017 - 04/2011
2Breast Neoplasms (Breast Cancer)
11/2012 - 04/2011
1Dyspnea (Shortness of Breath)
05/2017
1Fever (Fevers)
05/2017
1Nausea
05/2017
1Neutropenia
05/2017
1Syncope (Fainting)
05/2017
1Thrombocytopenia (Thrombopenia)
05/2017
1Sarcoma (Soft Tissue Sarcoma)
05/2013
1Melanoma (Melanoma, Malignant)
05/2013
1Adenocarcinoma of Lung
02/2013
1Triple Negative Breast Neoplasms
11/2012
1Carcinogenesis
04/2011
1Lymphatic Metastasis
04/2011

Drug/Important Bio-Agent (IBA)

3Proteins (Proteins, Gene)FDA Link
05/2014 - 04/2011
2p21-Activated KinasesIBA
05/2013 - 04/2011
2lactate dehydrogenase 1 (LDH1)IBA
02/2013 - 11/2012
2Phosphotransferases (Kinase)IBA
12/2012 - 04/2011
2Phenobarbital (Luminal)FDA Link
11/2012 - 04/2011
1GDC-0425IBA
05/2017
1Checkpoint Kinase 1IBA
05/2017
1GemcitabineFDA Link
05/2017
1Alanine Transaminase (SGPT)IBA
05/2017
1Biomarkers (Surrogate Marker)IBA
05/2017
1Small Nuclear Ribonucleoproteins (snRNP)IBA
05/2014
1RibonucleoproteinsIBA
05/2014
1PF 3758309IBA
05/2013
1dabrafenibIBA
05/2013
1Mitogen-Activated Protein KinasesIBA
05/2013
1Therapeutic UsesIBA
05/2013
1VemurafenibIBA
05/2013
1Small Interfering RNA (siRNA)IBA
02/2013
1TOR Serine-Threonine KinasesIBA
12/2012
1Lactic Acid (Lactate)FDA LinkGeneric
11/2012
1Estrogens (Estrogen)FDA Link
11/2012
1Progesterone Receptors (Progesterone Receptor)IBA
11/2012
1Cyclin-Dependent Kinases (cdk Proteins)IBA
04/2012
1GTP Phosphohydrolases (GTPases)IBA
04/2011
1Protein Serine-Threonine Kinases (Protein-Serine-Threonine Kinase)IBA
04/2011

Therapy/Procedure

1Therapeutics
11/2012